Showing posts with label diabetes. Show all posts
Showing posts with label diabetes. Show all posts

Sunday, April 1, 2012

Another slice of cake?

I'm watching CBS 60 minutes with Dr Sanjay Gupta telling us how sugar is poisonous and speaking to a doctor who is recommending that men eat less that 150 calories worth of added sugar per day, while women eat less than 100.  The report is interesting; the effects of just s sip of soda stimulates the same part of the brain as hard drugs like cocaine, and continued consumption of sugar lead to a tolerance similar to that experienced by drug addicts. In other words, the more  you eat, the more you are driven to eat.  The chemical at the heart of this is not picky.  However we get dopamine to release from brain cells, be in sex, drugs or rock and roll or now... sugar, we are driven to need more.   OK, so we eat a lot of sugar. So what?  As long as we reduce our fats, red meats, bacon, chips etc, we are basically OK- correct?  As long as we control our weight somewhat, and lay off the chips we should be fine- right? Not even remotely.  A study being discussed on the show, took young adults and carefully controlled their diets for a period of time while monitoring their physiology and biochemistry.  They had blood drawn and were scanned throughout the study period which had them eating a non-added-sugar diet for the first few days of the study, followed by a diet with 25% of their calories in the form of sugar; still a relatively low amount of sugar by American standards (on average we consume about a third of a pound a day).  Blood samples were drawn every 30 minutes and the added- sugar consumers showed significant increases in small dense LDL cholesterol (the bad kind that clogs the arteries) within two weeks of eating the diet with 25% sugar.   For those old enough, you might remember that in the 70s the government restricted fat in the diet.
There was a short term benefit, likely due to increased awareness of dietary causes of disease and the number of people who reduced their intake of saturated fates.  However, the effect was not sustained.  Doctors not he show suggested we have replaced that fat with carbohydrates, and refined sugar in particular.  As one researcher pointed out, food without fat tastes like cardboard, so the food industry upped the sugar content to keeps palates satisfied.  Now, cardiovascular disease is back on the increase and our children may be the first generation to have a lower life expectancy that their parents.

So the sugar in our diet does as least as much harm to our cardiovascular health as fat, and maybe more. But the story doesn't end there.  Obvious effects of increased sugar are obesity, metabolic syndrome, and diabetes, and all of these diseases have peripheral effects.  Less obvious is the effect of sugar on some cancers. Because sugar stimulates increases in insulin, it also catalyzed the growth of certain types of cancers.  Almost a third of common human cancers contain insulin receptors that circulating sugar latches onto and triggers the tumor cells to take up the glucose to use for cell growth.  Basically the tumor cells highjack our blood sugar and uses it to feed itself and grow.  Exactly whether the sugars in the blood cause the tumor to begin or just nudge it along once it has become established makes no difference.  Sugar is good news for cancer, and bad news for us.

There is much more to the sugar story that I'll save for other blogs but as we think about how to balance our diets, it's worth thinking about the role of the food industry in our food choices.  Since I still have the TV on, I'm catching a few ads I haven't seen before.  In one, Con Agra is encouraging us to buy their products and is promising one meal for a hungry child for ever specially marked package we buy.  This sounds incredible and I am sure there is good will behind the gesture. Certainly, there are too many hungry kids in America today. However, the foods that Con Agra is asking us to buy includes Snack Paks, frozen chicken nuggets, Chef Boyardee and others, all of which are high in sugar.  We buy and eat a package of processed food that will go a little way towards poisoning us (some might think that's too strong a word but based on what I have read and hear, I don't think so) and in return Con Agra will feed a child.  Does this make anyone wonder exactly how they will be feeing that child?

And finally, as I complete this blog, I just saw a fantastic commercial on the TV with a diverse group of vibrant people stripping open their coats and cardigans to unveil bright red shirts with 'I'm unique', I'm A Vailable, I'm a dreamer....etc, as they run, walk, dance, around some city. It seemed like such a positive commercial, celebrating all that is good in the world- courage, difference, creativity.  Imagine my disappointment when I realized what the ad was for.   Dr Pepper.  Ugh.

Thursday, February 7, 2008

Physiologists-come back-all is forgiven

Google this story.....Diabetes Study Partially Halted After Deaths

Published: February 7, 2008 New York Times

...and you will be amazed. Apparently lowering blood sugar in Type II diabetics (90% of the diabetic population have Type II) increases your chance of dying. It was supposed to be the other way around. This is a quick post so I'll get to the point. Perhaps the physiology of the diabetic patient is fundamentally different to that of a non-diabetic? This is not a radical statement, nor a novel one, but the pharmaceutical profession do tend to think of a diseased individual as a person having 'normal' physiology with an 'abnormal' disease superimposed on it. So, we just add drugs, or drug cocktails, to 'fix' all the abnormal bits (for eg the high sugar, or the high cholesterol). Most drugs are assessed by their effects on receptors and organs rather than whole systems as they go through drug development. They are marketing in the same manner. No wonder we tend to pile up the meds to counter all the deviant aspects of a person's physiology rather than stepping back to assess the overall picture. The 'overall picture' is a scary concept. Modern medicine doesn't give us the tools to assess nor treat it.
In the current age of high profile drug cocktail-related deaths such as the recent passing of Heath Ledger, and Ann Nicole Smith, perhaps it is time for those of us in the health professions to think of how we can begin to see the human as an ever evolving system over the years, that becomes fundamentally changed as we reach the tipping point for various disease states (diabetes is only one--dementia, autoimmune disorders, depression, anxiety etc, etc are others). When we do become diabetic, depressed, etc, our baselines have changed. And, because we are an interconnected mess of tissues and cells, these baselines affect every aspect of our being from our response to drugs to our mental view of the world. We can't just keep throwing on more meds until the blood sugar is low enough, or we feel calm and serene enough to get back to work. It's time we spent more time looking at the heart of our diseases and the dynamic physiology that underpins them; that complex backdrop that determines our unique response to everything that interacts with us, natural or imposed.